Percentage concentration (March 2026 NMC update)

Site: Computer Based Test (CBT) Provided by ONT Global Academy
Course: Part A Numeracy
Book: Percentage concentration (March 2026 NMC update)
Printed by: Guest user
Date: Sunday, 6 September 2026, 2:20 PM

1. Percentage concentration

With NMC recent CBT exam update (March 2026) percentage concentration question might be asked in your NMC CBT exam.

Let us have a look how the percentage % (w/v) calculation works. 

Drug concentration may also be measured as percentage % (w/v). Percentage means the number of grams of drug dissolved in 100ml solution, i.e. g per 100ml. This is irrespective of the size of the vial or bottle of fluid: e.g. Dextrose 5% infusions means that there are 5 grams of Dextrose dissolved in each 100ml of fluid, and this will remain the same if we have a 500ml infusion bag or a 1 litre infusion bag.

1 litre of 10% Dextrose means 10 gram Glucose in every 100 mL

Example-1,

Dextrose 50% injection in a 25ml vial. Patient prescribed 20g. How many mL?

50 % = 50 g in 100 mL

20 ÷ 50 x 100 

Answer: 40 mL

Example-2,

Calcium Chloride 10% injection in a 10ml ampoule. How much is needed for a patient prescribed 2g?

10 % = 10 g in 100 mL

Apply formula,

Dose required ÷ Dose available x volume

÷ 10 x 100 = 20 mL (i. e. 2 ampoules)


One in ….. concentration

This final type of concentration method is used only occasionally, e.g. tuberculin, adrenaline. 1 is stated as 1 in 100, 1 in 10,000, etc, and means grams in ml. 

Thus: 1 in 100 means 1g in 100ml 

1 in 1000 means 1g in 1000ml 

1 in 10,000 means 1g in 10,000ml 

Therefore, it can be seen that 1 in 1000 is a WEAKER strength that 1 in 100, and 1 in 10,000 is WEAKER than 1 in 1000. 

Example: We want to give 1mg tuberculin using 1 in 1000 strength solution.


1 in 1000 strength solution means 1 g in 1000

Apply formula,

Dose required ÷ Dose available x Volume its in

1mg ÷ 1000mg x 1000 =  1 mL


Example-1,

Give 1mg of epinephrine using the 1 in 10,000 solution.

1 in 10,000 means 1g in 10,000 mL, 

i.e. 1000 mg in 10,000 mL

Apply formula,

Dose required ÷ Dose available x Volume its in

1mg ÷ 1000mg x 10,000 = 10 mL


Example-2,

Give 5mg tuberculin using 1 in 100 solution

1 in 100 means 1g in 100 ml, 

in mg, 1000 mg in 100 mL

Apply formula,

Dose required ÷ Dose available x Volume its in

5mg ÷ 1000mg x 100  

= 0.5 mL